Have researchers identified how to slow the progression of MS?07/02/2020
A group of scientists working in the university of Montreal Hospital Research Centre, believe they have discovered a way to block the progression of MS.
In a healthy brain the blood-brain barrier protects the brain from B lymphocyte cells, a type of white blood cell, however, with MS this barrier is compromised. The Scientists in Montreal, using mice and human cells (under glass), showed that by blocking a molecule called Activated Leukocyte Cell Adhesion Molecule, they were able to lessen the amount of B lymphocyte cells crossing the barrier into the brain and slow down the progression of MS.
Currently B-cell directed therapies do exist but, at present, they deplete all B cells which leaves people susceptible to infections and even cancer.
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